Imaging Protocols in Clinical Studies in Advanced Age-Related Macular Degeneration: Recommendations from Classification of Atrophy Consensus Meetings

Abstract

Purpose To summarize the results of 2 consensus meetings (Classification of Atrophy Meeting [CAM]) on conventional and advanced imaging modalities used to detect and quantify atrophy due to late-stage non-neovascular and neovascular age-related macular degeneration (AMD) and to provide recommendations on the use of these modalities in natural history studies and interventional clinical trials. Design Systematic debate on the relevance of distinct imaging modalities held in 2 consensus meetings. Participants A panel of retina specialists. Methods During the CAM, a consortium of international experts evaluated the advantages and disadvantages of various imaging modalities on the basis of the c..