Suitability of Nitinol Electrodes in Neural Prostheses such as Endovascular Neural Interfaces

Yan T Wong; Nicholas L Opie; Sam E John; Giulia Gerboni; Gil S Rind; Stephen M Ronayne; Kate E Fox; Thomas J Oxley; David B Grayden

Conference Proceedings

Suitability of Nitinol Electrodes in Neural Prostheses such as Endovascular Neural Interfaces

Yan T Wong, Nicholas L Opie, Sam E John, Giulia Gerboni, Gil S Rind, Stephen M Ronayne, Kate E Fox, Thomas J Oxley, David B Grayden, J Patton (ed.), R Barbieri (ed.), J Ji (ed.), E Jabbari (ed.), S Dokos (ed.), R Mukkamala (ed.), D Guiraud (ed.), E Jovanov (ed.), Y Dhaher (ed.), D Panescu (ed.), M Vangils (ed.) Show all

2016 38TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC) | IEEE | Published : 2016

DOI: 10.1109/EMBC.2016.7591718

Abstract

A major challenge facing neural prostheses is the development of electrodes that are well tolerated by the brain and body. A novel way to circumvent the need to perform an invasive craniotomy and penetration of the blood-brain barrier to implant electrodes, is to guide electrodes up into the cerebral veins and place electrodes on the vessel walls adjacent to neuronal populations. To aid in the development of these stent based devices, microelectrodes manufactured from Nitinol would allow electrodes to be implanted via a catheter and then once deployed, alter their shape to conform to the vessel walls. However, there is a paucity of data on whether Nitinol is a suitable material to record neu..

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University of Melbourne Researchers

Nicholas Opie Author Medicine - Royal Melbourne Hospital

Thomas Oxley Author Medicine - Royal Melbourne Hospital

Sam John Author Biomedical Engineering

Stephen Ronayne Author Medicine - Royal Melbourne Hospital

David Grayden Author Biomedical Engineering

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Grants

Awarded by Australian Research Council's

Awarded by National Health and Medical Research Council of Australia

Awarded by Development Grant

Funding Acknowledgements

The authors would like to thank T. Vale and C. May for surgical assistance. This research was supported by the Australian Research Council's Discovery Projects funding scheme (DP140104533) and the National Health and Medical Research Council of Australia Project Grant APP1062532 and Development Grant APP1075117.