MDMA-induced neurotoxicity of serotonin neurons involves autophagy and rilmenidine is protective against its pathobiology

Linda D Mercer; Gavin C Higgins; Chew L Lau; Andrew J Lawrence; Philip M Beart

Journal article

MDMA-induced neurotoxicity of serotonin neurons involves autophagy and rilmenidine is protective against its pathobiology

Linda D Mercer, Gavin C Higgins, Chew L Lau, Andrew J Lawrence, Philip M Beart

Neurochemistry International | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2017

DOI: 10.1016/j.neuint.2017.01.010

University of Melbourne Researchers

Linda Lau Author Florey Department of Neuroscience and Mental Health

Philip Beart Author Florey Department of Neuroscience and Mental Health

Andrew Lawrence Author Florey Department of Neuroscience and Mental Health

Related Projects (3)

Unravelling mitochondrial contributions to neuronal injury

Mitochondria are components of cells normally providing energy for essential functions and in the energy demanding brain, under stress condi..

RESEARCH FELLOWSHIP

My research focuses on understanding pathobiological mechanisms in acute and chronic neurodegenerative conditions such as stroke and Parkins..

RESEARCH FELLOWSHIP

I am a neuroscientist, studying fundamental mechanisms related to addiction. A major feature of my research is the neuropharmacological char..

Grants

Awarded by NHMRC

Funding Acknowledgements

The authors thank Servier (Paris) for generously providing rilmenidine. The advice of Dr Verena Wimmer is greatly appreciated. Supported in part by the NH&MRC Grant APP509217. PMB and AJL are supported by a NH&MRC Research Fellowships APP1020401 and APP1020737, respectively. The Morey Institute of Neuroscience and Mental Health receives infrastructure support from the Victorian State Government (Australia).