Journal article

Optimization of propagation-based x-ray phase-contrast tomography for breast cancer imaging

P Baran, S Pacile, YI Nesterets, SC Mayo, C Dullin, D Dreossi, F Arfelli, D Thompson, D Lockie, M McCormack, ST Taba, F Brun, M Pinamonti, C Nickson, C Hall, M Dimmock, F Zanconati, M Cholewa, H Quiney, PC Brennan Show all

Physics in Medicine and Biology | IOP Publishing Ltd | Published : 2017

Abstract

The aim of this study was to optimise the experimental protocol and data analysis for in-vivo breast cancer x-ray imaging. Results are presented of the experiment at the SYRMEP beamline of Elettra Synchrotron using the propagation-based phase-contrast mammographic tomography method, which incorporates not only absorption, but also x-ray phase information. In this study the images of breast tissue samples, of a size corresponding to a full human breast, with radiologically acceptable x-ray doses were obtained, and the degree of improvement of the image quality (from the diagnostic point of view) achievable using propagation-based phase-contrast image acquisition protocols with proper incorpor..

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