Journal article

The Beneficial Effects of Physical Activity: Is It Down to Your Genes? A Systematic Review and Meta-Analysis of Twin and Family Studies

JR Zadro, D Shirley, TB Andrade, KJ Scurrah, A Bauman, PH Ferreira

Sports Medicine - Open | SPRINGER | Published : 2017


BACKGROUND: There is evidence for considerable heterogeneity in the responsiveness to regular physical activity (PA) which might reflect the influence of genetic factors. The aim of this systematic review was to assess whether the response to a PA intervention for measures of body composition and cardiorespiratory fitness is (i) correlated within twin pairs and/or families and (ii) more correlated in monozygotic twins (MZ) compared to dizygotic twins (DZ), which would be consistent with genetic effects. METHODS: We performed electronic database searches, combining key words relating to "physical activity" and "genetics", in MEDLINE, CINAHL, EMBASE, SPORTS Discuss, AMED, PsycINFO, WEB OF SCIE..

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Funding Acknowledgements

There was no funding for this study. KJS is funded in part by a Centre of Research Excellence Grant from the National Health and Medical Research Council of Australia.