The Feasibility of At-Home iPad Cognitive Testing For Use in Clinical Trials.
Dorene M Rentz, Maria Dekhtyar, Julia Sherman, Samantha Burnham, Deborah Blacker, Sarah L Aghjayan, Kathryn V Papp, Rebecca E Amariglio, Adrian Schembri, Tanya Chenhall, Paul Maruff, Paul Aisen, Bradley T Hyman, Reisa A Sperling
The Journal of Prevention of Alzheimer's Disease | Published : 2016
BACKGROUND: Technological advances now make it feasible to administer cognitive assessments at-home on mobile and touch-screen devices such as an iPad or tablet computer. Validation of these techniques is necessary to assess their utility in clinical trials. OBJECTIVES: We used a Computerized Cognitive Composite for Preclinical Alzheimer's Disease (C3-PAD) developed for iPad 1) to determine the feasibility of performing the C3-PAD at home by older individuals without the presence of a trained psychometrician; 2) to explore the reliability of in-clinic compared to at-home C3-PAD performance and 3) to examine the comparability of C3-PAD performance to standardized neuropsychological tests. DES..View full abstract