Heart rate independent QT variability component can detect subclinical cardiac autonomic neuropathy in diabetes.
Mohammad H Imam, Chandan K Karmakar, Ahsan H Khandoker, Herbert F Jelinek, M Palaniswami
Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) | Published : 2016
Cardiac autonomic neuropathy (CAN) may lead to life threatening arrhythmia due to denervation of both the parasympathetic and sympathetic branches of autonomic nervous system innervating the heart. CAN is a frequently under diagnosed complication of diabetes, because a patient can have asymptomatic CAN for several years before it is clinically apparent. However, detection of CAN at the early or subclinical stage leads to more effective treatment outcomes. Cardiac autonomic reflex tests (CART) (i.e. Ewing test battery) are normally used for the detection and staging of CAN. These tests have limitations with the necessity of active participation of the patients for test maneuvers, as a majorit..View full abstract