Magnetic resonance spectroscopy in seizure disorders

Abstract

Introduction The official International League Against Epilepsy classification divides epilepsy into generalized and partial (focal or localization related) seizures. In generalized epilepsy (accounting for approximately 40% of cases), the epileptic discharge begins simultaneously over both cerebral hemispheres, presumed to reflect an underlying diffuse abnormality. In focal epilepsies (accounting for the majority of other cases), the discharge begins in a localized region, reflecting a lesion or other focal abnormality. Brain metabolism in genetic and acquired causes of seizures Generalized seizures appear to be largely inherited, whereas partial seizures are principally acquired. While thi..