Journal article

Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement

Nikaia Smith, Nicolas Pietrancosta, Sophia Davidson, Jacques Dutrieux, Lise Chauveau, Pasquale Cutolo, Michel Dy, Daniel Scott-Algara, Benedicte Manoury, Onofrio Zirafi, Isabelle McCort-Tranchepain, Thierry Durroux, Francoise Bachelerie, Olivier Schwartz, Jan Muench, Andreas Wack, Sebastien Nisole, Jean-Philippe Herbeuval

Nature Communications | NATURE PUBLISHING GROUP | Published : 2017

University of Melbourne Researchers

Grants

Awarded by European Consortium Oncornet (HORIZON MSCA-ITN-ETN-Project)


Awarded by SIDACTION


Awarded by Agence National de la Recherche sur le SIDA et les Hepatites


Awarded by UK Medical Research Council


Awarded by Francis Crick Institute from Cancer Research UK


Awarded by Agence nationale de Recherche (Investissements d'Avenir)


Awarded by Medical Research Council


Awarded by The Francis Crick Institute


Funding Acknowledgements

We thank Dr Lucie Barblu for her technical help, Jean-Maurice Petit at the Central Service for Microscopy (SCM) of Paris Descartes University for technical assistance and the Common Service of Flux Cytometry (S2C) of Paris Descartes University. Thanks are due to Cisbio Bioassays for providing us plasmids and fluorescent ligands to implement Tag lite assays. F.B. and T.D. are supported by the European Consortium Oncornet (HORIZON 2020 MSCA-ITN-2014-ETN-Project 641833 ONCORNET). We also thank Dr Olivier Neyrolles's and his team and particularly Dr Geanncarlo Lugo for technical discussion about siRNA in DC. This work was supported by SIDACTION and by the Agence National de la Recherche sur le SIDA et les Hepatites (ANRS DFAAP 2016-1 and SF/MB/no.817), by SIDACTION (AI21-1/01732), by the UK Medical Research Council (U117597139) and the Francis Crick Institute which receives its core funding from Cancer Research UK (FC001206) (S.D., A.W.), as well as the Agence nationale de Recherche (Investissements d'Avenir-ANR-10-LABX-0033-LERMIT) grant (F.B., P.C.) and fellowship (P.C.).