Journal article

Treatment of nondysgerminomatous ovarian germ cell tumors: an analysis of 69 cases.

PL Mitchell, N Al-Nasiri, R A'Hern, C Fisher, A Horwich, CR Pinkerton, JH Shepherd, C Gallagher, M Slevin, P Harper, R Osborne, J Mansi, T Oliver, ME Gore

Cancer | Published : 1999

Abstract

BACKGROUND: Combination chemotherapy has dramatically improved the prognosis of patients with nondysgerminomatous ovarian germ cell tumors (NDOGCT). However, guidelines are needed for the identification of patients at risk of relapse. METHODS: The authors performed a retrospective analysis of women with NDOGCT managed during the period 1970-1994 at the Royal Marsden Hospital and other hospitals of the London Gynaecological Oncology Group. RESULTS: Sixty-nine women were included; their median follow-up was 5.7 years (minimum, 12 months). The median age was 21 years (range, 4-44 years), with a histology of immature teratoma (IT) for 17 patients, endodermal sinus tumor (EST) for 20 patients, an..

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