Journal article

Monoclonal antibody therapy for the treatment of asthma and chronic obstructive pulmonary disease with eosinophilic inflammation

John Nixon, Paul Newbold, Tomas Mustelin, Gary P Anderson, Roland Kolbeck

PHARMACOLOGY & THERAPEUTICS | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2017

DOI: 10.1016/j.pharmthera.2016.10.016

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University of Melbourne Researchers

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ANTICALINS: INHALABLE BIOLOGICALS FOR SEVERE ASTHMA

This grant aims to develop a new class of medicines called 'anticalins'. Anticalins behave like a successful class of medicines called monoc..

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Funding Acknowledgements

Editing assistance was provided by Elizabeth Strickland, PhD, of JK Associates, Conshohocken, PA, and Michael A. Nissen, ELS, of AstraZeneca, Gaithersburg, MD. This assistance was funded by AstraZeneca, Gaithersburg, MD, USA.

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Keywords

Science & Technology
Antibodies, Monoclonal
Neonatal Fc-Receptor
Colony-Stimulating Factor
Pharmacology & Pharmacy
Cytokines
Bone-Mineral Density
Chronic Obstructive Pulmonary Disease
Life Sciences & Biomedicine
Receptors, Interleukin-5
Animals
Biologic Therapy
Asthma
Messenger-Rna Expression
Interleukins
Interleukin-5
Respiratory Function Tests
Airway Inflammation
Prednisone-Dependent Asthma
Recombinant Human Interleukin-5
Innate Lymphoid-Cells
Anti-Asthmatic Agents
Humans
Sputum Eosinophils
Nitric-Oxide Levels
Inflammation
Eosinophils
Pulmonary Disease, Chronic Obstructive