Journal article

Defining the Geographical Range of the Plasmodium knowlesi Reservoir

CL Moyes, AJ Henry, N Golding, Z Huang, B Singh, JK Baird, PN Newton, M Huffman, KA Duda, CJ Drakeley, IRF Elyazar, NM Anstey, Q Chen, Z Zommers, S Bhatt, PW Gething, SI Hay

Plos Neglected Tropical Diseases | PUBLIC LIBRARY SCIENCE | Published : 2014

Abstract

Background:The simian malaria parasite, Plasmodium knowlesi, can cause severe and fatal disease in humans yet it is rarely included in routine public health reporting systems for malaria and its geographical range is largely unknown. Because malaria caused by P. knowlesi is a truly neglected tropical disease, there are substantial obstacles to defining the geographical extent and risk of this disease. Information is required on the occurrence of human cases in different locations, on which non-human primates host this parasite and on which vectors are able to transmit it to humans. We undertook a systematic review and ranked the existing evidence, at a subnational spatial scale, to investiga..

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University of Melbourne Researchers

Grants

Awarded by Fogarty International Center


Funding Acknowledgements

CLM and AJH are supported by the Wellcome Trust [091835]. NG is funded by a Bill & Melinda Gates Foundation grant [OPP1053338]. ZH is funded by the Vector-Borne Disease Network. PNN is funded by the Wellcome Trust of Great Britain. MH is funded by the Asia Africa Science Platform Program of the Japan Society for the Promotion of Science and Grants-In-Aid for Overseas Research, Japanese Ministry of Education Science awarded to Shusuke Nakazawa. CJD is funded by a ESEI/UKRC programme grant on Plasmodium knowlesi [G1100796]. IRFE is supported by a Wellcome Trust Research Training Fellowship [B9RZGS0]. NMA is supported by a National Health and Medical Research Council Practitioner Fellowship. PWG is a Medical Research Council Career Development Fellow [K00669X] and receives support from the Bill and Melinda Gates Foundation [OPP1068048] that also supports SB. SIH is funded by a Senior Research Fellowship from the Wellcome Trust that also supports KAD [095066]. SIH also acknowledges support from the RAPIDD program of the Science & Technology Directorate, Department of Homeland Security, and the Fogarty International Center, National Institutes of Health (http://www.fic.nih.gov). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.