Journal article

A non-canonical function of Ezh2 preserves immune homeostasis

Ajithkumar Vasanthakumar, Dakang Xu, Aaron TL Lun, Andrew J Kueh, Klaas PJM van Gisbergen, Nadia Iannarella, Xiaofang Li, Liang Yu, Die Wang, Bryan RG Williams, Stanley CW Lee, Ian J Majewski, Dale I Godfrey, Gordon K Smyth, Warren S Alexander, Marco J Herold, Axel Kallies, Stephen L Nutt, Rhys S Allan

EMBO Reports | WILEY | Published : 2017


Awarded by National Natural Science Foundation of China

Awarded by National Basic Research Program of China

Funding Acknowledgements

We thank David Tarlinton, Amanda Light, Simon Willis, Jane Visvader, Marnie Blewitt, and Sarah Kinkel from the Walter and Eliza Hall Institute and Nicholas Williamson (Bio21 University of Melbourne) for technical assistance, advice, and discussions. We also thank Alexander Tarakhovsky (Rockefeller University) for the Ezh2<SUP>fl/fl</SUP> mice and Stuart Orkin (DFCI, Harvard) for the Eed<SUP>fl/fl</SUP> mice. This work was supported by grants and fellowships from the National Health and Medical Research Council of Australia (RSA, SLN, WSA, GKS, AK, BRGW, DX, DIG), the Australian Research Council (RSA, SLN, AK), the Sylvia and Charles Viertel Foundation (AK), an American Asthma Foundation Grant (SLN, RSA), the National Natural Science Foundation of China (DX) (81273247, 81472655, and 31670905), the National Basic Research Program of China (2012CB911204), and the Netherlands Organization for Scientific Research (KPJvG). This study was made possible through Victorian State Government Operational Infrastructure Support and Australian Government NHMRC Independent Research Institute Infrastructure Support scheme and the Australian Cancer Research Fund.