Journal article
Maternal Chorioamnionitis and Postneonatal Respiratory Tract Infection in Ex-Preterm Infants
DP Burgner, D Doherty, J Humphreys, A Currie, K Simmer, A Charles, T Strunk
Journal of Pediatrics | MOSBY-ELSEVIER | Published : 2017
Abstract
Objective To assess whether exposure to histologically confirmed chorioamnionitis (ie, histologic chorioamnionitis [HCA]) is associated with altered risk of infection-related hospitalization (IRH) during the first 24 months of life in very preterm infants. Study design This single-center retrospective cohort study analyzed data on 1218 infants born at <30 weeks gestational age (GA). Semiquantitative placental histology, obstetric, and neonatal data were extracted from hospital databases and linked with discharge diagnoses on rehospitalization until age 24 months from statewide statutory data. The associations between HCA and overall and clinical categories of IRH were analyzed by Cox proport..
View full abstractGrants
Awarded by Royal Australasian College of Physicians
Funding Acknowledgements
Supported by an AstraZeneca Fellowship of the Royal Australasian College of Physicians (to T.S.). D.B. is supported by an Australian National Health and Medical Research Council (NHMRC) Fellowship (APP1064629) and is an Honorary Future Leader Fellow of the National Heart Foundation of Australia. Research at Murdoch Childrens Research Institute is supported by the Victorian Government's Operational Infrastructure Support Program. Research at the Centre for Neonatal Research and Education is supported by the NHMRC Centre of Research Excellence (APP1057514, to K.S., T.S., and D.B.). The authors declare no conflicts of interest.