Koala retrovirus genotyping analyses reveal a low prevalence of KoRV-A in Victorian koalas and an association with clinical disease.
Alistair R Legione, Jade LS Patterson, Pam Whiteley, Simon M Firestone, Megan Curnick, Kate Bodley, Michael Lynch, James R Gilkerson, Fiona M Sansom, Joanne M Devlin
J Med Microbiol | Published : 2017
PURPOSE: Koala retrovirus (KoRV) is undergoing endogenization into the genome of koalas in Australia, providing an opportunity to assess the effect of retrovirus infection on the health of a population. The prevalence of KoRV in north-eastern Australia (Queensland and New South Wales) is 100 %, whereas previous preliminary investigations in south-eastern Australia (Victoria) suggested KoRV is present at a lower prevalence, although the values have varied widely. Here, we describe a large study of free-ranging koalas in Victoria to estimate the prevalence of KoRV and assess the clinical significance of KoRV infection in wild koalas. METHODOLOGY: Blood or spleen samples from 648 koalas where t..View full abstract