Stereotactic Ablative Body Radiotherapy for the Treatment of Spinal Oligometastases

Abstract

Aims To report multicentre outcomes of patients with spinal oligometastases treated with stereotactic ablative body radiotherapy (SABR). The primary objective was to estimate the widespread failure-free survival (WFFS) at 2 years – defined as freedom from metastases not amenable to local salvage therapy and death. Materials and methods Patients with one to three metastases treated with spinal SABR between January 2010 and July 2014 at four academic institutions were included in this retrospective review. The median dose/fractionation was 24 Gy (range 16–52.5 Gy) in two fractions (range one to three) and the median biologically effective dose (α/β = 10) was 52.5 Gy (range 40–144.4 Gy). The WF..