Meta-Analysis of the Effectiveness of Heart Transplantation in Patients With a Failing Fontan.
Nazlee Tabarsi, Meijiao Guan, Jacob Simmonds, Mustafa Toma, Marla Kiess, Victor Tsang, Peter Ruygrok, Igor Konstantinov, William Shi, Jasmine Grewal
The American Journal of Cardiology | Published : 2017
The Fontan procedure is increasingly being used to palliate univentricular physiology. It is a complex anatomic and physiologic repair that can fail at any age, often leaving heart transplantation as the only remaining solution. A meta-analysis was performed to achieve the aim of systematically evaluating the existing evidence for survival after heart transplantation in patients who have undergone a Fontan palliation. MEDLINE, Embase, PubMed, and Web of Science were searched for original research studies. The primary outcome was mortality at 1 and 5 years after transplantation. Five hundred eighty-two records were screened, after the removal of duplicates, 12 retrospective observational stud..View full abstract