Journal article
Exploring the effect of lactium™ and zizyphus complex on sleep quality: A double-blind, randomized placebo-controlled trial
A Scholey, S Benson, A Gibbs, N Perry, J Sarris, G Murray
Nutrients | MDPI | Published : 2017
DOI: 10.3390/nu9020154
Abstract
Acute, non-clinical insomnia is not uncommon. Sufferers commonly turn to short-term use of herbal supplements to alleviate the symptoms. This placebo-controlled, double-blind study investigated the efficacy of LZComplex3 (lactium™, Zizyphus, Humulus lupulus, magnesium and vitamin B6), in otherwise healthy adults with mild insomnia. After a 7-day single-blind placebo run-in, eligible volunteers (n = 171) were randomized (1:1) to receive daily treatment for 2 weeks with LZComplex3 or placebo. Results revealed that sleep quality measured by change in Pittsburgh Sleep Quality Index (PSQI) score improved in both the LZComplex3 and placebo groups. There were no significant between group difference..
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Funding Acknowledgements
The authors would like to thank the study participants. This study was sponsored by Sanofi Consumer Healthcare Pty Ltd. (Macquarie Park, NSW, Australia). Jim Sockler of Datapharm Australia Pty Ltd. (Drummoyne, NSW, Australia) developed the statistical analysis plan and analysed the data. Editorial assistance in the preparation of this manuscript was provided by Adrianna Kalous and Hazel Palmer, ISMPP CMPP<SUP>TM</SUP> of Scripitx Pty Ltd. (Freshwater, NSW, Australia) and sponsored by Sanofi Consumer Healthcare Pty Ltd. The authors were responsible for all content, interpretation of the data and the decision to publish the results; they received no honoraria related to the development of this manuscript.