Physical and Nutritional Prehabilitation in Older Patients with Colorectal Carcinoma: A Systematic Review

Abstract

Background and Purpose: Sarcopenia and malnourishment are highly prevalent in older patients with colorectal cancer (CRC), who form a growing group of patients at risk of adverse outcome after surgery. Intervention on physical function and/or nutritional status may decrease the risk of postoperative complications. However, the overall effect of preoperative physical and nutritional interventions (better known as prehabilitation) in older patients with CRC remains unknown. The objective was to review the literature on physical and nutritional prehabilitation performed as observational cohort studies or randomized controlled trials in patients 60 years and older undergoing elective CRC surgery..