Journal article
Proton chemical shift imaging of the brain in pediatric and adult developmental stuttering
J O'Neill, Z Dong, R Bansal, I Ivanov, X Hao, J Desai, E Pozzi, BS Peterson
JAMA Psychiatry | AMER MEDICAL ASSOC | Published : 2017
Abstract
IMPORTANCE: Developmental stuttering is a neuropsychiatric condition of incompletely understood brain origin. Our recent functional magnetic resonance imaging study indicates a possible partial basis of stuttering in circuits enacting self-regulation of motor activity, attention, and emotion. OBJECTIVE: To further characterize the neurophysiology of stuttering through in vivo assay of neurometabolites in suspect brain regions. DESIGN, SETTING, AND PARTICIPANTS: Proton chemical shift imaging of the brain was performed in a case-control study of children and adults with and without stuttering. Recruitment, assessment, and magnetic resonance imaging were performed in an academic research settin..
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Awarded by National Institute of Mental Health
Funding Acknowledgements
This study was funded by the Millhiser Family Trust, grant K02 74677 from the National Institute of Mental Health, the Suzanne Crosby Murphy endowment at Columbia University, and Children's Hospital Los Angeles.