Journal article

Differential control of cardiac functions by the brain

Lauren M Salo, Ruy R Campos, Robin M McAllen

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY | WILEY | Published : 2006

Abstract

1. The idea is introduced that cardiac rate, contractility or atrioventricular (A-V) conduction spread may be controlled independently by the brain. Limited data from reflex studies are cited to support this view. 2. Evidence is presented that individual autonomic post- and preganglionic neurons have quite specific actions on the heart. Premotor and other central neurons can have preferential actions on heart rate, contractility or A-V conduction. 3. The functional implications of selective cardiac control are discussed.