Journal article

Cell population heterogeneity and evolution towards drug resistance in cancer: Biological and mathematical assessment, theoretical treatment optimisation

Rebecca H Chisholm, Tommaso Lorenzi, Jean Clairambault

Biochimica et Biophysica Acta (BBA) - General Subjects | ELSEVIER SCIENCE BV | Published : 2016

DOI: 10.1016/j.bbagen.2016.06.009

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Keywords

Epigenetic Landscape
Phenotype
Drug Resistance
Dna Methylation
Nongenetic Instability
Tumor Heterogeneity
Drug Resistance, Neoplasm
Immunotherapy
Evolution
Somatic Mutation
Cancer Therapeutics
Heterogeneity
Humans
Stem-Cells
Clonal Evolution
Optimal Control
Biophysics
Biochemistry & Molecular Biology
Life Sciences & Biomedicine
Intratumoral Heterogeneity
Chronic Myeloid-Leukemia
Cancer Cell Populations
Models, Theoretical
Neoplasms
Science & Technology
Circadian Clock
Models, Biological