Journal article
A systematic evaluation of intraoperative white matter tract shift in pediatric epilepsy surgery using high-field MRI and probabilistic high angular resolution diffusion imaging tractography
JYM Yang, R Beare, ML Seal, AS Harvey, VA Anderson, WJ Maixner
Journal of Neurosurgery Pediatrics | Published : 2017
Abstract
OBJECTIVE: Characterization of intraoperative white matter tract (WMT) shift has the potential to compensate for neuronavigation inaccuracies using preoperative brain imaging. This study aimed to quantify and characterize intraoperative WMT shift from the global hemispheric to the regional tract-based scale and to investigate the impact of intraoperative factors (IOFs). METHODS: High angular resolution diffusion imaging (HARDI) diffusion-weighted data were acquired over 5 consecutive perioperative time points (MR1 to MR5) in 16 epilepsy patients (8 male; mean age 9.8 years, range 3.8-15.8 years) using diagnostic and intraoperative 3-T MRI scanners. MR1 was the preoperative planning scan. MR2..
View full abstractGrants
Awarded by State Government of Victoria
Funding Acknowledgements
This research was conducted within the Department of Neurosurgery, Royal Children's Hospital, and the Developmental Imaging research group, Murdoch Childrens Research Institute at the Melbourne Children's MRI Centre, Melbourne, Victoria. It was supported by the Royal Children's Hospital Foundation (RCH1000 to Dr. Yang), Australia's National Health and Medical Research Council (Postgraduate Scholarship 1039160 to Dr. Yang), Murdoch Childrens Research Institute, The University of Melbourne Department of Paediatrics, and the Victorian Government's Operational Infrastructure Support Program.