Journal article

Motor Speech Phenotypes of Frontotemporal Dementia, Primary Progressive Aphasia, and Progressive Apraxia of Speech

Matthew L Poole, Amy Brodtmann, David Darby, Adam P Vogel

JOURNAL OF SPEECH LANGUAGE AND HEARING RESEARCH | AMER SPEECH-LANGUAGE-HEARING ASSOC | Published : 2017

Abstract

Purpose: Our purpose was to create a comprehensive review of speech impairment in frontotemporal dementia (FTD), primary progressive aphasia (PPA), and progressive apraxia of speech in order to identify the most effective measures for diagnosis and monitoring, and to elucidate associations between speech and neuroimaging. Method: Speech and neuroimaging data described in studies of FTD and PPA were systematically reviewed. A meta-analysis was conducted for speech measures that were used consistently in multiple studies. Results: The methods and nomenclature used to describe speech in these disorders varied between studies. Our meta-analysis identified 3 speech measures which differentiate va..

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Grants

Funding Acknowledgements

We would like to note the following roles each author had in contributing to this article: Matthew L. Poole designed the study, analyzed and interpreted the data, and drafted the manuscript; Amy Brodtmann interpreted the data and revised the manuscript; David Darby interpreted the data and revised the manuscript; and Adam P. Vogel designed and conceptualized the study, analyzed and interpreted the data, and revised the manuscript. Matthew L. Poole would like to acknowledge the postgraduate scholarship support from the National Health and Medical Research Council of Australia.