TDP-43 mutations causing amyotrophic lateral sclerosis are associated with altered expression of RNA-binding protein hnRNP K and affect the Nrf2 antioxidant pathway

Diane Moujalled; Alexandra Grubman; Karla Acevedo; Shu Yang; Yazi D Ke; Donia M Moujalled; Clare Duncan; Aphrodite Caragounis; Nirma D Perera; Bradley J Turner; Mercedes Prudencio; Leonard Petrucelli; Ian Blair; Lars M Ittner; Peter J Crouch; Jeffrey R Liddell; Anthony R White

Journal article

TDP-43 mutations causing amyotrophic lateral sclerosis are associated with altered expression of RNA-binding protein hnRNP K and affect the Nrf2 antioxidant pathway

Diane Moujalled, Alexandra Grubman, Karla Acevedo, Shu Yang, Yazi D Ke, Donia M Moujalled, Clare Duncan, Aphrodite Caragounis, Nirma D Perera, Bradley J Turner, Mercedes Prudencio, Leonard Petrucelli, Ian Blair, Lars M Ittner, Peter J Crouch, Jeffrey R Liddell, Anthony R White

Human Molecular Genetics | OXFORD UNIV PRESS | Published : 2017

DOI: 10.1093/hmg/ddx093

University of Melbourne Researchers

Nirma Perera Author Florey Department of Neuroscience and Mental Health

Bradley Turner Author Florey Department of Neuroscience and Mental Health

Diane Moujalled Author Medical Biology (W.E.H.I.)

Jeffrey Liddell Author Pharmacology and Therapeutics

Peter Crouch Author Pharmacology and Therapeutics

Grants

Funding Acknowledgements

Motor Neuron Disease Research Institute of Australia (Terry Quinn, Cliff Smith MND Research Grants) (ARW), Australian Rotary Health (JJ), Orion-Farmos Research Foundation (KMK), and Stafford Fox Medical Research Foundation (BJT).