Host immunity to Plasmodium falciparum and the assessment of emerging artemisinin resistance in a multinational cohort
Ricardo Ataide, Elizabeth A Ashley, Rosanna Powell, Jo-Anne Chan, Michael J Malloy, Katherine O'Flaherty, Eizo Takashima, Christine Langer, Takafumi Tsuboi, Arjen M Dondorp, Nicholas P Day, Mehul Dhorda, Rick M Fairhurst, Pharath Lim, Chanaki Amaratunga, Sasithon Pukrittayakamee, Tinh Hien Tran, Ye Htut, Mayfong Mayxay, M Abul Faiz Show all
Proceedings of the National Academy of Sciences | NATL ACAD SCIENCES | Published : 2017
Awarded by National Health and Medical Research Council of Australia
Awarded by Australian Research Council
Awarded by Ramaciotti Establishment Grant
We thank all the patients for their participation in these studies; TRAC study investigators; Bongkot Soonthornsata and Daniel Blessborn for their assistance in specimen management; Annie Mo (NIH) for providing EBA175RII; Robin Anders (La Trobe University) for providing MSP2; Alistair McLean, Jack Richards, and Andrew Guy for technical support; and Paul Newton and colleagues in Laos and TRAC investigators and colleagues in Cambodia for their efforts in support of this work. Antibody work and analysis was supported by the National Health and Medical Research Council of Australia [Project Grant 1060785 (to F.J.I.F., J.A.S., and F.N.), Program Grant APP637406 (to J.G.B.), training fellowship 637396 (to F.J.I.F.), and senior research fellowships APP1077636 (to J.G.B.) and 1104975 (J.A.S.)], the Australian Research Council [Future Fellowships FT130101122 (to F.J.I.F.) and FT0992317 (to J.G.B.)], Ramaciotti Establishment Grant 3245/2011 and Ian Potter Foundation Grant (to F.J.I.F.), and a Victorian State Government Operational Infrastructure Support grant. The clinical trials were funded by the UK Department for International Development, with additional support from the Worldwide Antimalarial Resistance Network and the Intramural Research Program of the National Institute of Allergy and Infectious Diseases, NIH. The trials were part of the Wellcome Trust Mahidol Oxford Tropical Medicine Research Programme funded by the Wellcome Trust of Great Britain. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.