Conference Proceedings
Clinical evaluation of glimepiride versus glyburide in NIDDM in a double-blind comparative study
DG Dills, J Schneider, SL Aronoff, MA Azorr, D Brunner, WT Cefalu, AJ Cohen, J Cyrus, Z Freedman, BL Haag, BP Hamilton, TW Littlejohn, CP Lucas, JS Matlock, JB McGill, SS Miller, T Nikolai, JT Ogilvie, DA Podlecki, M Ricaurte Show all
Hormone and Metabolic Research | Published : 1996
Abstract
We report on the results of a one-year, multicenter, randomized, double-blind, parallel-group titration study of the new sulfonylurea agent, glimepiride, versus use of non-micronized glyburide to treat 577 patients with non-insulin dependent diabetes mellitus (NIDDM). Similar decreases in both fasting plasma glucose and HbA1C were found using glimepiride and glyburide. There was a lower incidence of hypoglycemia with glimepiride than glyburide.