Therapy in cerebrovascular disease: Current status and future directions

Abstract

OBJECTIVE: To assess the current status and future directions of therapy in cerebrovascular disease. DATA SOURCES: English language literature search using MEDLINE, Index Medicus, reviews, texts and relevant papers. STUDY SELECTION: Information has been drawn from approximately 200 articles. DATA EXTRACTION AND SYNTHESIS: Those articles with most relevance to current practice and future directions in the therapy of cerebrovascular disease have been cited. CONCLUSIONS: Much progress has been made over the last 30 years in the therapy of primary and secondary prevention of cerebrovascular disease. The introduction of antihypertensive agents has been largely responsible for the decline in morta..