Journal article

EEG-triggered echo-planar functional MRI in epilepsy.

S Warach, JR Ives, G Schlaug, MR Patel, DG Darby, V Thangaraj, RR Edelman, DL Schomer

Neurology | Published : 1996


We investigated whether: (1) EEG recordings could be successfully performed in an MRI imager, (2) subclinical epileptic discharges could be used to trigger ultrafast functional MRI images, (3) artifact-free functional MRI images could be obtained while the patient was having the EEG monitored, and (4) the functional MRI images so obtained would show focal signal increases in relation to epileptic discharges. We report our results in two patients who showed focally higher signal intensity, reflective of increased local blood flow, in ultrafast functional MRI timed to epileptic discharges recorded while the patients were in the imager and compared with images not associated with discharges. On..

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