Journal article

Use of restenting should be minimized with intracoronary radiation therapy for in-stent restenosis.

Dong-Hun Cha, Ishtiaq A Malik, Edouard Cheneau, Andrew E Ajani, Laurent Leborgne, Roswitha Wolfram, Michael Porrazzo, Lowell F Satler, Kenneth M Kent, Augusto D Pichard, Ellen Pinnow, Joseph Lindsay, Ron Waksman

Catheterization and Cardiovascular Interventions | Published : 2003


Restenting at the time of intracoronary radiation therapy (IRT) for in-stent restenosis (ISR) potentially increases the risk of late total occlusion (LTO) of the treated vessel. Prolonged antiplatelet therapy with clopidogrel (6 months) has been shown to be effective in reducing LTO risk. The purpose of this study was to assess the impact of restenting on clinical outcomes following IRT for ISR with 6 months of clopidogrel. We retrospectively evaluated 1,275 patients with 6-months clinical follow-up who were enrolled in radiation trials for ISR using gamma- and beta-emitters conducted at Washington Hospital Center. Patients were analyzed according to whether additional stents were deployed a..

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University of Melbourne Researchers