Journal article
Use of population based background rates of disease to assess vaccine safety in childhood and mass immunisation in Denmark: Nationwide population based cohort study
TA Rasmussen, MRS Jørgensen, S Bjerrum, S Jensen-Fangel, H Støvring, L Østergaard, OS Søgaard
BMJ Online | BMJ PUBLISHING GROUP | Published : 2012
DOI: 10.1136/bmj.e5823
Abstract
Objectives: To predict the number of selected outcomes temporally associated but not caused by vaccination, to aid causality assessment of adverse events arising after mass immunisation in a paediatric population. Design: Nationwide population based cohort study. Setting: Denmark. Participants: All liveborn infants delivered after 1 January 1980. Study population was followed from date of birth until hospital admission for selected outcome diagnoses, death, first emigration, age 18 years, or 31 December 2009. The study population was subject to vaccines used in standard childhood immunisation in Denmark, with 82-93% vaccine coverage. Main outcome measures: Incidence of acute infectious and p..
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Funding Acknowledgements
[ "The study was funded by the Department of Infectious Diseases, Aarhus University Hospital, Denmark.", "All authors have completed the Unified Competing Interest form at www.icmje.org/coi_disclosure.pdf (available on request from the corresponding author) and declare: support from Aarhus University Hospital for the submitted work; no financial relationships with any organisations that might have an interest in the submitted work in the previous 3 years; no other relationships or activities that could appear to have influenced the submitted work." ]