Stimulus-Responsiveness and Drug Release from Porous Silicon Films ATRP-Grafted with Poly(N-isopropylacrylamide)
Roshan B Vasani, Steven JP McInnes, Martin A Cole, Abdul Mutalib Md Jani, Amanda V Ellis, Nicolas H Voelcker
LANGMUIR | AMER CHEMICAL SOC | Published : 2011
In this report, we employ surface-initiated atom transfer radical polymerization (SI-ATRP) to graft a thermoresponsive polymer, poly(N-isopropylacrylamide) (PNIPAM), of controlled thickness from porous silicon (pSi) films to produce a stimulus-responsive inorganic-organic composite material. The optical properties of this material are studied using interferometric reflectance spectroscopy (IRS) above and below the lower critical solution temperature (LCST) of the PNIPAM graft polymer with regard to variation of pore sizes and thickness of the pSi layer (using discrete samples and pSi gradients) and also the thickness of the PNIPAM coatings. Our investigations of the composite's thermal switc..View full abstract
The authors would like to thank the South Australian Premier's Science and Research Council for providing funding for this work.