Journal article

Systematic Review Links the Prevalence of Intraductal Carcinoma of the Prostate to Prostate Cancer Risk Categories

Laura H Porter, Mitchell G Lawrence, Dragan Ilic, David Clouston, Damien M Bolton, Mark Frydenberg, Declan G Murphy, Carmel Pezaro, Gail P Risbridger, Renea A Taylor

European Urology | ELSEVIER | Published : 2017


Intraductal carcinoma of the prostate (IDC-P) is associated with poor prognosis. While it is often regarded as a rare pathology, the prevalence of IDC-P remains unclear, with variable reports from small and disparate patient populations. To determine how common IDC-P is across the spectrum of prostate cancer, we conducted a systematic review correlating IDC-P prevalence with prostate cancer risk. Electronic searches of the OVID Medline, PubMed, and Scopus literature databases identified 38 patient cohorts in 24 articles, which were divided between four prostate cancer risk categories (low, moderate, high, and recurrent or metastatic disease). This review, which included radical prostatectomy..

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Awarded by National Health and Medical Research Council of Australia

Awarded by Victorian Cancer Agency

Funding Acknowledgements

This work was supported by funding from the National Health and Medical Research Council of Australia (fellowship 1035721 to M.G.L., fellowship 1102752 to G.P.R., project grant 1077799), the Victorian Cancer Agency (fellowship MCRF15023 to R.A.T., CAPTIV programme), the Peter and Lyndy White Foundation, and the EJ Whitten Foundation. The sponsors played a role in the design and conduct of the study.