Water, Sanitation and Hygiene (WASH) and environmental risk factors for soil-transmitted helminth intensity of infection in Timor-Leste, using real time PCR
Suzy J Campbell, Susana V Nery, Rebecca Wardell, Catherine A D'Este, Darren J Gray, James S McCarthy, Rebecca J Traub, Ross M Andrews, Stacey Llewellyn, Andrew J Vallely, Gail M Williams, Archie CA Clements
PLoS Neglected Tropical Diseases | PUBLIC LIBRARY SCIENCE | Published : 2017
BACKGROUND: No investigations have been undertaken of risk factors for intensity of soil-transmitted helminth (STH) infection in Timor-Leste. This study provides the first analysis of risk factors for intensity of STH infection, as determined by quantitative PCR (qPCR), examining a broad range of water, sanitation and hygiene (WASH) and environmental factors, among communities in Manufahi District, Timor-Leste. METHODS: A baseline cross-sectional survey of 18 communities was undertaken as part of a cluster randomised controlled trial, with additional identically-collected data from six other communities. qPCR was used to assess STH infection from stool samples, and questionnaires administere..View full abstract
ACAC is an Australian National Health and Medical Research Council (NHMRC) Senior Research Fellow (1058878), JSM is an Australian NHMRC Practitioner Fellow, and DJG is an Australian NHMRC Career Development Fellow. This work is funded by an NHMRC Partnership project in collaboration with WaterAid Australia. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.