Structure and Biosynthesis of Isatropolones, Bioactive Amine-Scavenging Fluorescent Natural Products from Streptomyces Go66

Xiaofeng Cai; Yi-Ming Shi; Nicole Poehlmann; Ole Revermann; Isabel Bahner; Sacha J Pidot; Frank Wesche; Helmut Lackner; Claudia Buechel; Marcel Kaiser; Christian Richter; Harald Schwalbe; Timothy P Stinear; Axel Zeeck; Helge B Bode

Journal article

Structure and Biosynthesis of Isatropolones, Bioactive Amine-Scavenging Fluorescent Natural Products from Streptomyces Go66

Xiaofeng Cai, Yi-Ming Shi, Nicole Poehlmann, Ole Revermann, Isabel Bahner, Sacha J Pidot, Frank Wesche, Helmut Lackner, Claudia Buechel, Marcel Kaiser, Christian Richter, Harald Schwalbe, Timothy P Stinear, Axel Zeeck, Helge B Bode

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | WILEY-V C H VERLAG GMBH | Published : 2017

DOI: 10.1002/anie.201701223

University of Melbourne Researchers

Tim Stinear Author Microbiology and Immunology

Sacha Pidot Author Microbiology and Immunology

Related Projects (1)

NEW ANTBIOTICS FROM OLD MICROBES

Once treatable infections are becoming deadly because bacteria are developing broad antibiotic resistance. New medicines are urgently needed..

Grants

Awarded by ERC starting grant

Awarded by European Community

Awarded by National Health and Medical Research Council (NHMRC) of Australia

Funding Acknowledgements

Work in the Bode group was supported by the DFG and an ERC starting grant (Grant 311477) as well as by the European Community's Seventh Framework Program (FP7/2007-2013; Grant Agreement No. 602773), which also supported M.K. Y.-M.S. is supported by a Postdoctoral Research Fellowship from the Alexander von Humboldt Foundation. Genome sequencing in the Stinear group was supported by a grant from the National Health and Medical Research Council (NHMRC) of Australia (1105522). Work at the BMRZ is supported by the state of Hesse. H.S. is member of the DFG cluster of excellence "Macromolecular Complexes".