Mortality Reduction for Fever, Hyperglycemia, and Swallowing Nurse-Initiated Stroke Intervention QASC Trial (Quality in Acute Stroke Care) Follow-Up
Sandy Middleton, Kelly Coughlan, George Mnatzaganian, Nancy Low Choy, Simeon Dale, Asmara Jammali-Blasi, Chris Levi, Jeremy M Grimshaw, Jeanette Ward, Dominique A Cadilhac, Patrick McElduff, Janet E Hiller, Catherine D'Este
STROKE | LIPPINCOTT WILLIAMS & WILKINS | Published : 2017
BACKGROUND AND PURPOSE: Implementation of nurse-initiated protocols to manage fever, hyperglycemia, and swallowing dysfunction decreased death and disability 90 days poststroke in the QASC trial (Quality in Acute Stroke Care) conducted in 19 Australian acute stroke units (2005-2010). We now examine long-term all-cause mortality. METHODS: Mortality was ascertained using Australia's National Death Index. Cox proportional hazards regression compared time to death adjusting for correlation within stroke units using the cluster sandwich (Huber-White estimator) method. Primary analyses included treatment group only unadjusted for covariates. Secondary analysis adjusted for age, sex, marital status..View full abstract
Awarded by National Health and Medical Research Council (NHMRC)
This study was funded by an Australian Catholic University Faculty of Health Sciences grant. The original QASC Trial was funded by a National Health and Medical Research Council (NHMRC) Project Grant 353803 (2005-2010).