Associations between hip bone mineral density, aortic calcification and cardiac workload in community-dwelling older Australians
AJ Rodriguez, D Scott, A Hodge, DR English, GG Giles, PR Ebeling
OSTEOPOROSIS INTERNATIONAL | SPRINGER LONDON LTD | Published : 2017
In older adults, lower bone density in the proximal femur was associated with increased heart burden, and this association was linked to calcification in the aorta. These results were seen in women but not in men. PURPOSE: To determine whether there is an association between lower bone mineral density (BMD) and increased cardiac workload in older adults, and if this association was independent of abdominal aortic calcification (AAC). METHODS: Three hundred thirty-seven participants [mean ± SD age = 70 ± 5 years and BMI = 28 ± 5 kg/m2, 61% females] had BMD determined by dual-energy X-ray absorptiometry and AAC determined by radiography. Aortic calcification score (ACS) was determined visually..View full abstract
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Awarded by Australian NHMRC grants
MCCS cohort recruitment was funded by VicHealth and Cancer Council Victoria. The MCCS was further supported by Australian NHMRC grants 209057, 251553 and 504711 and by infrastructure provided by Cancer Council Victoria. Cases and their vital status were ascertained through the Victorian Cancer Registry (VCR) and the Australian Institute of Health and Welfare (AIHW), including the National Death Index and the Australian Cancer Database. AJR was supported by an Australian Government Research Training Programme Scholarship. DS is support by an Australian Government National Health and Medical Research Council RD Wright Biomedical Career Development Fellow. The authors would like to acknowledge Dr. Belal Khan and Dr. Nayab Khan for their efforts in recruitment for this study, calcification scoring and in database preparation.