Journal article

The Not-So-Good Prognosis of Streptococcal Periprosthetic Joint Infection Managed by Implant Retention: The Results of a Large Multicenter Study

Jaime Lora-Tamayo, Eric Senneville, Alba Ribera, Louis Bernard, Michel Dupon, Valerie Zeller, Ho Kwong Li, Cedric Arvieux, Martin Clauss, Ilker Uckay, Dace Vigante, Tristan Ferry, Jose Antonio Iribarren, Trisha N Peel, Parham Sendi, Nina Gorisek Miksic, Dolors Rodriguez-Pardo, Maria Dolores del Toro, Marta Fernandez-Sampedro, Ulrike Dapunt Show all



BACKGROUND.: Streptococci are not an infrequent cause of periprosthetic joint infection (PJI). Management by debridement, antibiotics, and implant retention (DAIR) is thought to produce a good prognosis, but little is known about the real likelihood of success. METHODS.: A retrospective, observational, multicenter, international study was performed during 2003-2012. Eligible patients had a streptococcal PJI that was managed with DAIR. The primary endpoint was failure, defined as death related to infection, relapse/persistence of infection, or the need for salvage therapy. RESULTS.: Overall, 462 cases were included (median age 72 years, 50% men). The most frequent species was Streptococcus ag..

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Awarded by Instituto de Salud Carlos III (Spanish Ministry of Economy and Competitiviness)

Funding Acknowledgements

J. L.-T holds a clinical research contract "Sara Borrell" (CD14/00176) from the Instituto de Salud Carlos III (Spanish Ministry of Economy and Competitiviness). CRIOGO is funded by the French Ministry of Health. A. R. was supported by a research grant from the Bellvitge Biomedical Research Institute (IDIBELL). REIPI is supported by the Spanish Ministry of Economy and Competititviness, Instituto de Salud Carlos III, and by the European Development Regional Fund "A way to achieve Europe."