Journal article

Measuring prediction capacity of individual verbs for the identification of protein interactions

Dietrich Rebholz-Schuhmann, Antonio Jimeno-Yepes, Miguel Arregui, Harald Kirsch

Journal of Biomedical Informatics | ACADEMIC PRESS INC ELSEVIER SCIENCE | Published : 2010

Abstract

MOTIVATION: The identification of events such as protein-protein interactions (PPIs) from the scientific literature is a complex task. One of the reasons is that there is no formal syntax to denote such relations in the scientific literature. Nonetheless, it is important to understand such relational event representations to improve information extraction solutions (e.g., for gene regulatory events). In this study, we analyze publicly available protein interaction corpora (AIMed, BioInfer, BioCreAtIve II) to determine the scope of verbs used to denote protein interactions and to measure their predictive capacity for the identification of PPI events. Our analysis is based on syntactical langu..

View full abstract