Journal article

Redefining phenotypes in eating disorders based on personality: A latent profile analysis

Isabel Krug, Tammy Root, Cynthia Bulik, Roser Granero, Eva Penelo, Susana Jimenez-Murcia, Fernando Fernandez-Aranda



To conduct a latent profile analysis (LPA) in eating disorder (ED) patients using temperament and character (TCI-R) measures as indicators. 1312 ED patients including those with anorexia nervosa (AN), bulimia nervosa (BN) and EDNOS were assessed. The final LPA solution was validated using demographics, clinical variables, ED symptomatology (EDI-2) and impulsive behaviors. The best-fitting model consisted of a six-profile solution using the seven subscales of the TCI-R. These profiles were labeled: "self-focused", "inhibited", "average", "impulsive", "adaptive" and "maladaptive". Validation analyses indicated that the "inhibited" and "maladaptive" profiles generally presented with the highest..

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Awarded by Fondo de Investigation Sanitaria-FIS

Awarded by AGAUR

Awarded by European Commission

Awarded by National Institute of Health

Awarded by European Community

Funding Acknowledgements

Financial support was received from Fondo de Investigation Sanitaria-FIS (PI081573; PI081714) and AGAUR (2009SGR1554). It was also partially supported by the European Commission under the Seventh Framework Programme (FP7-ICT-215839-2007-Playmancer project). CIBER Fisiopatologia de la Obesidad y Nutrition (CIBERobn) is an initiative of ISCIII. Dr. Root was supported by National Institute of Health grant T32MH076694. Dr. Krug was supported by a Marie Curie Intra European Fellowship within the 7th European Community Framework Programme, as No. 254774 (call reference: FP7-PEOPLE-2009-IEF).