Journal article

Immunohistochemical demonstration of serotonin in nerves supplying human cerebral and mesenteric blood-vessels. Some speculations about their involvement in vascular disorders.

SG Griffith, G Burnstock

The Lancet | Published : 1983


Serotonin (5-hydroxytryptamine, 5-HT) can produce vasoconstriction or vasodilatation and has been implicated in the pathogenesis of many vascular disorders. Nerves containing 5-HT were demonstrated by immunofluorescence histochemistry in fetal cerebral and mesenteric blood-vessels.