American Gastroenterological Association medical position statement: Celiac Sprue.

Abstract

Celiac sprue is a life-long inflammatory condition of the gastrointestinal tract that affects the small intestine in genetically susceptible individuals. The prevalence in Northern Europe is approximately 1:300, whereas in the United States it occurs less frequently. A small intestinal biopsy is mandatory to confirm the diagnosis. Treatment involves a strict gluten-free diet that excludes wheat, rye, and barley and that should be supervised by a dietician. Follow-up is important because of potential long-term complications.