Journal article

A stemness-related ZEB1-MSRB3 axis governs cellular pliancy and breast cancer genome stability

Anne-Pierre Morel, Christophe Ginestier, Roxane M Pommier, Olivier Cabaud, Emmanuelle Ruiz, Julien Wicinski, Mojgan Devouassoux-Shisheboran, Valerie Combaret, Pascal Finetti, Christelle Chassot, Christiane Pinatel, Frederique Fauvet, Pierre Saintigny, Emilie Thomas, Caroline Moyret-Lalle, Joel Lachuer, Emmanuelle Despras, Jean-Luc Jauffret, Francois Bertucci, Jerome Guitton Show all

Nature Medicine | NATURE PUBLISHING GROUP | Published : 2017

University of Melbourne Researchers

Grants

Awarded by Ligue Nationale contre le Cancer


Awarded by Lyon Integrated Research Institute in Cancer (LYRIC)


Awarded by Institut National contre le Cancer


Awarded by Cancer-DGOS grant


Awarded by Marseille Integrated Research Institute in Cancer


Funding Acknowledgements

The authors thank I. Treilleux and G. Clapisson (Resource Biological Center) for providing tumor samples; N. Nazaret for sequencing analysis; P. Kannouche for providing help and laboratory space for the DNA-fiber spreading analysis; I. Iacono, S. Brejon, A. Pierrot, J. Perrossier and S. Croze for technical support; D. Negre (CIRI/EVIR) for providing the pWPIR-GFP lentiviral vector; C. Eaves (Terry Fox Laboratory) for providing cells; and M. Tommasino (IARC) for providing vectors. We thank the CRCM animal core facility for animal housing and the CRCM flow cytometry core (M.L. Thibullt) for technical assistance. We also thank B. Manship for critical reading of the manuscript. This work was supported by funding from the Ligue Nationale contre le Cancer (EL2011.LNCC/AP and EL2016.LNCC/AIP) and the Project National Cancer Association, Lyon Integrated Research Institute in Cancer (LYRIC, INCa 4664) to A.P. This work was additionally supported by funding from the Institut National contre le Cancer (project PLBio 2015-266) to P.S., the Institut National contre le Cancer (project PLBIO12-007) to E.D., a Cancer-DGOS grant (TRANSLA11-103) to E.C.-J. and the Marseille Integrated Research Institute in Cancer (INCa 6038) to D.B.