Journal article
Total and beverage-specific alcohol intake and the risk of aggressive prostate cancer: a case–control study
NP Papa, RJ MacInnis, H Jayasekara, DR English, D Bolton, ID Davis, N Lawrentschuk, JL Millar, J Pedersen, G Severi, MC Southey, JL Hopper, GG Giles
Prostate Cancer and Prostatic Diseases | NATURE PUBLISHING GROUP | Published : 2017
DOI: 10.1038/pcan.2017.12
Abstract
Background:: Ethanol in alcoholic beverages is a known carcinogen, but its association with aggressive prostate cancer (APC) is uncertain. Recent studies have shown a modest increase in risk of APC associated with heavy alcohol intake while association for beverage types remain inconsistent. Methods:: Using a case–control design and self-administered questionnaire, we examined the association between APC (high grade and/or advanced stage) and frequency and quantity of alcohol intake 2 years prior to enrolment. Furthermore, we delineated the relationships for beverage-specific intakes of beer, red wine, white wine and spirits. Results:: The study included 1282 APC cases and 951 controls. Beer..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
This study was funded in part by NHMRC grant #623204. IDD is supported by an Australian National Health and Medical Research Council Practitioner Fellowship (APP1102604).