Journal article

Accuracy of PECARN, CATCH, and CHALICE head injury decision rules in children: a prospective cohort study

Franz E Babl, Meredith L Borland, Natalie Phillips, Amit Kochar, Sarah Dalton, Mary McCaskill, John A Cheek, Yuri Gilhotra, Jeremy Furyk, Jocelyn Neutze, Mark D Lyttle, Silvia Bressan, Susan Donath, Charlotte Molesworth, Kim Jachno, Brenton Ward, Amanda Williams, Amy Baylis, Louise Crowe, Ed Oakley Show all

LANCET | ELSEVIER SCIENCE INC | Published : 2017

Abstract

BACKGROUND: Clinical decision rules can help to determine the need for CT imaging in children with head injuries. We aimed to validate three clinical decision rules (PECARN, CATCH, and CHALICE) in a large sample of children. METHODS: In this prospective observational study, we included children and adolescents (aged <18 years) with head injuries of any severity who presented to the emergency departments of ten Australian and New Zealand hospitals. We assessed the diagnostic accuracy of PECARN (stratified into children aged <2 years and ≥2 years), CATCH, and CHALICE in predicting each rule-specific outcome measure (clinically important traumatic brain injury [TBI], need for neurological inter..

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Grants

Awarded by National Health and Medical Research Council


Awarded by Emergency Medicine Foundation


Awarded by Perpetual Philanthropic Services Australia


Awarded by Auckland Medical Research Foundation


Awarded by Health Research Council of New Zealand


Funding Acknowledgements

National Health and Medical Research Council, Emergency Medicine Foundation, Perpetual Philanthropic Services, WA Health Targeted Research Funds, Townsville Hospital Private Practice Fund, Auckland Medical Research Foundation, A + Trust.The study was funded by grants from the National Health and Medical Research Council (project grant GNT1046727, Centre of Research Excellence for Paediatric Emergency Medicine GNT1058560); the Murdoch Childrens Research Institute; the Emergency Medicine Foundation (EMPJ-11162); Perpetual Philanthropic Services (2012/1140) Australia; Auckland Medical Research Foundation (number 3112011); the A + Trust (Auckland District Health Board); WA Health Targeted Research Funds 2013; the Townsville Hospital and Health Service Private Practice Research and Education Trust Fund; and supported by the Victorian Government's Infrastructure Support Program. FEB's time was part funded by a grant from the Royal Children's Hospital Foundation, Melbourne, Australia. SRD's time was part funded by the Health Research Council of New Zealand (HRC13/556). We thank the participating families and emergency department staff at participating sites. We thank research staff from the following sites: Kaya Gardiner, Nicola Williams, Elle Goss, Triona Stephens, Marta Arpone, and Joseph Mabuti (The Royal Children's Hospital, Melbourne, VIC, Australia); Sharon O'Brien, Timothy Loy, Jeremy Rogers, Samantha Oosterhof, and Verity Watt (Princess Margaret Hospital, Perth, WA, Australia); Susan Montgomery (The Townsville Hospital, Townsville, QLD, Australia); Rebecca Saul, Meegan Price, Petrina Hetherington, Emily Casey, Mary Lang, Jane O'Shea, Anne Cook, Kerrie-Ann Abel, and Bronwyn Griffin (The Royal Children's Hospital, Brisbane, QLD, Australia); Tamara Brunton (Monash Medical Centre, Melbourne, VIC, Australia); Shirley Lawrence (Kidzfirst Children's Hospital, Middlemore, Auckland, New Zealand); Megan Bonisch (Starship Children's Hospital, Auckland, New Zealand); Carey Alymer and Simone Green (Women's and Children's Hospital Adelaide, SA, Australia); Laura Phillips and Elizabeth Moss (Children's Hospital Westmead, Sydney, NSW, Australia); and Meg Jepperson (Mater Children's Hospital, Brisbane, QLD, Australia).