Journal article

DOES RESPIRATORY VARIATION IN INFERIOR VENA CAVA DIAMETER PREDICT FLUID RESPONSIVENESS: A SYSTEMATIC REVIEW AND META-ANALYSIS

Elliot Long, Ed Oakley, Trevor Duke, Franz E Babl

Shock | LIPPINCOTT WILLIAMS & WILKINS | Published : 2017

Abstract

BACKGROUND: The aim of fluid resuscitation is to increase stroke volume, yet this effect is observed in only 50% of patients. Prediction of fluid responsiveness may allow fluid resuscitation to be administered to those most likely to benefit. The aim of this study was to systematically review the test characteristics of respiratory variation in inferior vena cava (IVC) diameter as a predictor of fluid responsiveness in patients with acute circulatory failure. METHODS: Electronic searches combined with reference review of identified studies. Prospective observational studies of all patient groups and ages that used a recognized reference standard, stratified participants into fluid responders..

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Grants

Awarded by National Health and Medical Research Council Centre of Research Excellence Grant for Pediatric Emergency Medicine, Canberra, ACT, Australia


Funding Acknowledgements

This study was supported in part by a National Health and Medical Research Council Centre of Research Excellence Grant for Pediatric Emergency Medicine (GNT1058560), Canberra, ACT, Australia, the Victorian Governments Infrastructure Support Program, Melbourne, Australia, a Shields Research Entry Scholarship provided by the Royal Australasian College of Physicians, Sydney, NSW, Australia, and by a Clinical Sciences Theme Grant provided by The Royal Children's Hospital Foundation, Melbourne, VIC, Australia. FEB was supported in part by a grant from the Royal Children's Hospital Foundation.