Integrative assessment of brain and cognitive function in post-traumatic stress disorder.
Melinda D Veltmeyer, C Richard Clark, Alexander C McFarlane, Kim L Felmingham, Richard A Bryant, Evian Gordon
J Integr Neurosci | Published : 2005
The present study combined neuropsychological and electrophysiological measures to obtain a comprehensive profile of the everyday attentional and memory dysfunction reported in PTSD. The event-related potential (ERP) literature has consistently found abnormalities in late components (N2, P3) reflecting working memory (WM) function. However, the neuropsychological profile reported in the literature has considerable variation. The present study examined ERP activity in 33 PTSD participants and matched controls during a standard two-tone auditory oddball task. Neuropsychological assessment was carried out using a task battery assessing a wide range of cognitive functions. Consistent with previo..View full abstract