Journal article
The Role of Brain Somatostatin in the Central Regulation of Feed, Water and Salt Intake in Sheep
K Sunagawa, RS Weisinger, MJ McKinley, BS Purcell, C Thomson, PL Burns
Asian Australasian Journal of Animal Sciences | Published : 2001
Abstract
The physiological role of brain somatostatin in the central regulation of feed intake in sheep was investigated through a continuous intracerebroventricular (ICV) infusion of somatostastin 1-28 (SRIF) at a small dose of 5 μg/0.2 ml/hr for 98.5 hours from day 1 to day 5. Sheep (n=5) were fed for 2 hours once a day, and water and 0.5 M NaCl solution were given ad libitum . Feed. water and salt intake were measured during ICV infusion of artificial cerebrospinal fluid (CSF) and SRIF The feed intake during SRIF infusion on days 2 to 5 increased significantly compared to that during CSF infusion. Water intake, when compared to that during CSF infusion. only increased significantly on day 4. NaCl ..
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