Journal article

Thc lumbar preganglionic sympathetic supply to rat tail and hindpaw

JA Rathner, RM McAllen

JOURNAL OF THE AUTONOMIC NERVOUS SYSTEM | ELSEVIER SCIENCE BV | Published : 1998

Abstract

The segmental origins of the preganglionic sympathetic neurons which control the circulation of the rat tail were investigated and compared with those that supply the hindpaw. The left ventral roots of the first, second and sometimes the third lumbar segments were stimulated with 2-min pulse trains in 10 male Sprague-Dawley rats, which were anaesthetised with urethane (1-1.5 g/kg i.v.) and paralysed with pancuronium. Rats were warmed to increase cutaneous blood flow, and vasoconstrictor responses were detected by thermocouples as stimulus-locked falls in skin temperature. Stimulating the L2 ventral root always vasoconstricted the tail: in 50% of the rats, it also vasoconstricted the ipsilate..

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