Journal article

Role of medical history in brain tumour development. Results from the international adult brain tumour study

B Schlehofer, M Blettner, S Preston-Martin, D Niehoff, J Wahrendorf, A Arslan, A Ahlbom, WN Choi, GG Giles, GR Howe, J Little, F Menegoz, P Ryan

INTERNATIONAL JOURNAL OF CANCER | WILEY | Published : 1999

Abstract

In an international population-based case-control study carried out in 8 centres in 6 countries, we investigated the role of specific medical conditions in the aetiology of brain tumours in adults. Recruited were 1,178 glioma and 331 meningioma cases and 2,493 age- and gender-matched population controls. Only medical conditions occurring at least 2 years before brain tumour diagnosis were considered. Relative risks (RRs) and 95% confidence intervals (CIs) were estimated using a conditional logistic regression model. Heterogeneity between centres was tested. No association between meningioma and previous medical conditions was observed. For glioma, there was an increased risk associated with ..

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